LARP1 polyclonal antibody

Product Description

LARP1 polyclonal antibody is available at gentaur for next week delivery

Background: La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 β, 14-3-3 γ, 14-3-3 θ and 14-3-3 . Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  LARP1 polyclonal antibody detects endogenous levels of LARP1 protein.

W4BiowMW:  163kDa

Reactivity: Human

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Alternative Name:

Western blot analysis:  Western blot analysis of extracts of various cell lines, using LARP1 Antibody at 1:1000 dilution.

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit