Product Description
Lamin A/C polyclonal antibody is available at gentaur for next week delivery
Background: Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Applications: WB IHC IF IP
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Lamin A polyclonal antibody detects endogenous levels of Lamin A protein.
W4BiowMW: ~ 69,78 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human Lamin A.Alternative Name:
Prelamin-A/C; Lamin-A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1; Lamin A; LaminA; Lamin-A; Lamin C; LaminC; Lamin-CWestern blot analysis: Western blot analysis of extracts of various cell lines, using Lamin A/C antibody.
Immunohistochemistry: Immunohistochemistry (IHC) analysis of Lamin A pAb in paraffin-embedded human breast tumor tissue.
Immunofluorescence analysis: Immunofluorescence analysis of Hela cells, using Lamin A polyclonal antibody
Host: Rabbit
Swiss-Prot: P02545
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