Lamin A/C (Phospho-S392) polyclonal antibody

Product Description

Lamin A/C (Phospho-S392) polyclonal antibody is available at gentaur for next week delivery

Background: Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.

Applications:  WB IHC IF

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  Lamin A/C (Phospho-S392) polyclonal antibody detects endogenous levels of Lamin A/C protein only when phosphorylated at Ser392.

W4BiowMW:  ~ 74, 65 kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic phosphopeptide derived from human Lamin A/C around the phosphorylation site of Serine 392.

Alternative Name:

Prelamin-A/C; Lamin-A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1; Lamin A; LaminA; Lamin-A; Lamin C; LaminC; Lamin-C

Western blot analysis:  Western blot (WB) analysis of Lamin A/C (Phospho-S392) polyclonal antibody at 1:500 dilution LaneA:DLD whole cell lysate LaneB:The Kidney tissue lysate of Mouse LaneC:The Lung tissue lysate of Rat

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: P02545

 

 

 

 

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