Product Description
KRAS polyclonal antibody is available at gentaur for next week delivery
Background: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.Defects in KRAS are a cause of acute myelogenous leukemia (AML). AML is a malignant disease in which hematopoietic precursors are arrested in an early stage of development. Defects in KRAS are a cause of juvenile myelomonocytic leukemia (JMML). JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. It is characterized by leukocytosis with tissue infiltration and in vitro hypersensitivity of myeloid progenitors to granulocyte-macrophage colony stimulating factor. Defects in KRAS are the cause of Noonan syndrome type 3 (NS3). Defects in KRAS are a cause of gastric cancer (GASC).
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: KRAS polyclonal antibody detects endogenous levels of KRAS protein.
W4BiowMW: ~ 22 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human KRAS.Alternative Name:
c Kirsten ras protein; c-K-ras; c-Ki-ras; Cellular c Ki ras2 proto oncogene; cK Ras; GTPase KRas; K RAS p21 protein; K RAS2A; K RAS2B; K RAS4A; K RAS4B; K-Ras 2; KI RAS; Ki-Ras; Kirsten rat sarcoma 2 viral (v Ki ras2) oncogene homolog; KRAS; KRAS1; KRAS2; N-terminally processed; NS; NS3; Oncogene KRAS2; PR310 cK ras oncogene; RASK; RASK2; Transforming protein p21; v Ki ras2 Kirsten rat sarcoma viral oncogene homolog;Western blot analysis: Western blot analysis of extracts of various cell lines, using KRAS antibody at 1:1000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 90s.
Immunohistochemistry: Immunofluorescence - KRAS Polyclonal Antibody
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P01116
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