Product Description
KIFAP3 polyclonal antibody is available at gentaur for next week delivery
Background: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
Applications: WB IP
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: KIFAP3 polyclonal antibody detects endogenous levels of KIFAP3 protein.
W4BiowMW: ~ 110 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human KIFAP3.Alternative Name:
FLA3; KAP3; SMAP; KAP-1; KAP-3; Smg-GDS; dJ190I16.1;Western blot analysis: Western blot analysis of KIFAP3 antibody.
Immunohistochemistry:
Immunofluorescence analysis: Immunoprecipitation analysis of 200ug extracts of HeLa cells, using 3 ug KIFAP3 antibody.
Host: Rabbit
Swiss-Prot: Q92845
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