Product Description
INTS6 polyclonal antibody is available at gentaur for next week delivery
Background: DICE1 (Deleted in Cancer 1) is a protein mapping to chromosome 13q14, which appears to be a tumor suppressor gene in non-small cell lung carcinoma. Expression of DICE1 is lost or downregulated in most non-small lung carcinomas compared to normal lung tissue. This is most likely due to a loss of heterozygosity (LOH) of chromosome 13, which is prone to deletions and rearrangements in human lung cancers. The DICE1 gene is extremely homologous to the mouse protein, DBI-1, at the carboxy terminus. DBI-1, when expressed at high levels, interferes with the mitogenic response to IGF-1. Both DICE1 and DBI-1 contain the highly conserved DEAD-box motif, which suggests that these proteins are involved in critical aspects of cellular function and regulation.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: INTS6 polyclonal antibody detects endogenous levels of INTS6 protein.
W4BiowMW: ~ 115 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human INTS6.Alternative Name:
Integrator complex subunit 6; Int6; DBI-1; Protein DDX26; Protein deleted in cancer 1; DICE1; INTS6; DBI1; DDX26; DDX26AWestern blot analysis: WesternBlot (WB) analysis of INTS6 polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9UL03
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