Product Description
INTS10 polyclonal antibody is available at gentaur for next week delivery
Background: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS10 (integrator complex subunit 10) is also known as INT10 and is a 710 amino acid protein that is localized to the nucleus. INTS10 is a component of the integrator complex and, as such, is thought to aid in the regulation of 3’-end processing of spliceosomal U1 and U2 snRNAs.
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: INTS10 polyclonal antibody detects endogenous levels of INTS10 protein.
W4BiowMW: ~ 70 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human INTS10.Alternative Name:
Integrator complex subunit 10; Int10; INTS10; C8orf35Western blot analysis: Western blot analysis of extracts of various cells, using INTS10 antibody.
Immunohistochemistry: Immunofluorescence analysis of A549 cell using INTS10 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9NVR2
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