Product Description
Integrin αV polyclonal antibody is available at gentaur for next week delivery
Background: The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several αV subfamily members, including αVβ3, αVβ5, αVβ1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Integrin αV polyclonal antibody detects endogenous levels of Integrin αV protein.
W4BiowMW: ~ 140 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human Integrin αV.Alternative Name:
Integrin alpha-V; Vitronectin receptor subunit alpha; CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain; ITGAV; MSK8; VNRAWestern blot analysis: Western blot analysis of Integrin αV polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P06756
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