IL1R2 polyclonal antibody

Product Description

IL1R2 polyclonal antibody is available at gentaur for next week delivery

Background: Non-signaling receptor for IL1A, IL1B and IL1RN. ReducesIL1B activities. Serves as a decoy receptor by competetive bindingto IL1B and preventing its binding to IL1R1. Also modulatescellular response through non-signaling association with IL1RAPafter binding to IL1B. IL1R2 (membrane and secreted forms)preferentially binds IL1B and poorly IL1A and IL1RN. The secretedIL1R2 recruits secreted IL1RAP with high affinity; this complexformation may be the dominant mechanism for neutralization of IL1Bby secreted/soluble receptors.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  IL1R2 polyclonal antibody detects endogenous levels of IL1R2 protein.

W4BiowMW:  ~ 45 kDa

Reactivity: Human,Rat,Mouse

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to Human IL1R2

Alternative Name:

Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII; IL1R2; IL1RB

Western blot analysis:  Western blot (WB) analysis of IL1R2 polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate(20µg) Lane2:HEK293T whole cell lysate(40µg) Lane3:The Kidney tissue lysate of Rat(40ug) Lane4:The Heart tissue lysate of Mouse(40ug)

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: P27930

 

 

 

 

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