Product Description
IL1 beta polyclonal antibody is available at gentaur for next week delivery
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IL1 beta polyclonal antibody detects endogenous levels of IL1 beta protein.
W4BiowMW: ~ 17,35kDa
Reactivity: Human, Mouse, Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human IL1 beta.Alternative Name:
IL-1;IL1-BETA;IL1F2;IL1 beta;IL1BWestern blot analysis: Western blot analysis of extracts of THP-1 cells, using IL1 beta antibody at 1:1000 dilution.THP-1 cells were treated by LPS (1 μg/mL) at 37℃ for 6 hours.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded rat lung using IL1 beta antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis: Immunofluorescence analysis of THP-1 cells using IL1 beta antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Host: Rabbit
Swiss-Prot: P01584
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