Product Description
HSF2 polyclonal antibody is available at gentaur for next week delivery
Background: HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HSF2 polyclonal antibody detects endogenous levels of HSF2 protein.
W4BiowMW: ~ 60 kDa
Reactivity: Human,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human HSF2.Alternative Name:
Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2; HSTF2Western blot analysis: Western blot analysis of HSF2 polyclonal antibody
Immunohistochemistry: Immunohistochemistry (IHC) analysis of HSF2 polyclonal antibody in paraffin-embedded Rat Liver tissue.
Immunofluorescence analysis: Immunofluorescence analysis of A549 cells, using HSF2 polyclonal antibody
Host: Rabbit
Swiss-Prot: Q03933
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