Product Description
Histone H4 (Acetyl-K12) polyclonal antibody is available at gentaur for next week delivery
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Histone H4 (Acetyl-K12) polyclonal antibody detects endogenous levels of Histone H4 protein only when acetylated at Lys12.
W4BiowMW: Refer to Figures
Reactivity: Human,Mouse,Rat,Other (Wide Range)
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic acetylated peptide around K12 of human Histone H4Alternative Name:
Western blot analysis: Immunohistochemistry of paraffin-embedded human appendix using Acetyl-Histone H4-K12 antibody.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P62805
"
