Product Description
HCLS1 polyclonal antibody is available at gentaur for next week delivery
Background: HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin. HS1 contains four cortactin repeats and a single SH3 domain. This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse. Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLCγ1. HS1 also plays an important role in platelet activation.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HCLS1 polyclonal antibody detects endogenous levels of HCLS1 protein.
W4BiowMW: ~ 72 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human HCLS1.Alternative Name:
Hematopoietic lineage cell-specific protein; Hematopoietic cell-specific LYN substrate 1 LckBP1; p75; HCLS1; HS1Western blot analysis: Western blot analysis of HCLS1 polyclonal antibody
Immunohistochemistry: Immunohistochemistry (IHC) analysis of HCLS1 polyclonal antibody in paraffin-embedded Human Rectal Cancer tissue.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P14317
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