Product Description
HAP1 polyclonal antibody is available at gentaur for next week delivery
Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HAP1 polyclonal antibody detects endogenous levels of HAP1 protein.
W4BiowMW: ~ 76 kDa
Reactivity: Mouse, Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HAP1.Alternative Name:
HAP1; HAP2; HIP5; HLP; hHLP1Western blot analysis: Western blot (WB) analysis of HAP1 polyclonal antibody at 1:1000 dilution. Lysates/proteins: 25ug per lane.
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P54257
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