GPR224 polyclonal antibody

Product Description

GPR224 polyclonal antibody is available at gentaur for next week delivery

Background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  FTO polyclonal antibody detects endogenous levels of FTO protein.

W4BiowMW:  ~ 58 kDa

Reactivity: Human,Rat,Mouse

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to Human FTO.

Alternative Name:

Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO;mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO; KIAA1752

Western blot analysis:  Western blot (WB) analysis of FTO polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate(40ug) LaneB:Hela whole cell lysate(40ug) LaneC:A549 whole cell lysate(40ug) LaneD:The rat lung lysate of Mouse(40ug) LaneE:The rat kindey lysate of Mouse(40ug)

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: Q9C0B1

 

 

 

 

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