Product Description
GPR217 polyclonal antibody is available at gentaur for next week delivery
Background: In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein.
Applications: WB
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Specificity: SCML2 polyclonal antibody detects endogenous levels of SCML2 protein.
W4BiowMW: ~ 77,93 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human SCML2.Alternative Name:
Sex comb on midleg-like protein 2; SCML2Western blot analysis: Western blot (WB) analysis of SCML2 polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:K562 whole cell lysate LaneC:A549 whole cell lysate LaneD:H1792 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9UQR0
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