Product Description
GPR211 polyclonal antibody is available at gentaur for next week delivery
Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/ threonine (Ser/Thr) protein kinases. The salt-inducible kinases (SIKs) are a family of related serine-threonine kinases and are key enzymes that modulate important processes such as steroid hormone biosynthesis and Insulin signaling in adipocytes. QSK, also known as L19 or SIK3 (salt-inducible kinase 3), is a 1,263 amino acid cytoplasmic protein belonging to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and the AMPK subfamily. Ubiquitously expressed, QSK consists of one protein kinase domain and a UBA domain. QSK is activated by 14-3-3 ζ and utilizes magnesium as a cofactor. QSK exists as three alternatively spliced isoforms.
Applications: WB IHC
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Specificity: QSK polyclonal antibody detects endogenous levels of QSK protein.
W4BiowMW: ~ 140 kDa
Reactivity: Human,Rat,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human QSK.Alternative Name:
Serine/threonine-protein kinase SIK3; Salt-inducible kinase 3; SIK-3; Serine/threonine-protein kinase QSK; SIK3; KIAA0999; QSK; L19Western blot analysis: Western blot (WB) analysis of QSK polyclonal antibody at 1:500 dilution LaneA:L02 whole cell lysate LaneB:MCF-7 whole cell lysate LaneC:A549 whole cell lysate LaneD:CT-26 whole cell lysate LaneE:PC12 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9Y2K2
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