Product Description
GPR198 polyclonal antibody is available at gentaur for next week delivery
Background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 20 (Ras-related protein Rab-20) is a 234 amino acid protein that localizes to the golgi apparatus and belongs to the Rab subfamily of small GTPases. Expressed in normal and cancerous pancreatic tissue, Rab 20 plays an important role in apical endocytosis and recycling and may be involved in the development of exocrine pancreatic adenocarcinomas.
Applications: WB IHC
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Specificity: RAB20 polyclonal antibody detects endogenous levels of RAB20 protein.
W4BiowMW: ~ 26 kDa
Reactivity: Human,Rat,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human RAB20.Alternative Name:
Ras-related protein Rab-20; RAB20Western blot analysis: Western blot (WB) analysis of RAB20 polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:H1792 whole cell lysate LaneC:BV2 whole cell lysate LaneD:MEF whole cell lysate LaneE:C6 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9NX57
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