Product Description
GPR192 polyclonal antibody is available at gentaur for next week delivery
Background: Mitochondrial pyruvate dehydrogenase (PDH) catalyzes the oxidative decarboxylation of pyruvate and plays a central role in the regulation of homeostasis of carbohydrate fuels in mammals. PDH activity is controlled by a phosphorylation/dephosphorylation cycle, phosphorylation leading to inactivation and dephosphorylation leading to reactivation of PDH. The phosphorylation of PDH is catalyzed by pyruvate dehydrogenase kinase (PDK), the activity of which is stimulated by the products of PDH catalysis. PDK1 consists of alpha and beta subunits; the kinase activity resides in the alpha subunit. Three PDK isoenzymes have been identified in humans (PDK1, 2 and 3) and two have been identified in rodent (PDK1 and 2).
Applications: WB
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Specificity: PDK1 polyclonal antibody detects endogenous levels of PDK1 protein.
W4BiowMW: ~ 49 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human PDK1.Alternative Name:
PDH kinase 1; PDK1; PDHK1Western blot analysis: Western blot (WB) analysis of PDK1 polyclonal antibody at 1:500 dilution LaneA:H1792 whole cell lysate LaneB:CT-26 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q15118
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