Product Description
GPR167 polyclonal antibody is available at gentaur for next week delivery
Background: Nuclear hormone receptors function as transcriptional activators when their cognate ligands are bound. Binding of the appropriate ligand induces a conformational change in the nuclear receptor, allowing it to interact with transcriptional coactivators. NRBF2 (Nuclear receptor-binding factor 2), also known as COPR (Comodulator of PPAR and RXR), is thought to act as a transcriptional coactivator by altering the activity of target nuclear receptors. Highly expressed in the liver, placenta and keratinocytes, NRBF2 can interact with at least 7 nuclear receptors including PPARα, PPARδ and PPARγ. In the presence of a bound ligand, NRBF2 can interact with nuclear receptors RARα, RARγ. and RXRα. NRBF2, which exists as two isoforms due to alternative splicing, is localized to both the nucleus and the cytoplasm.
Applications: WB
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NRBF2 polyclonal antibody detects endogenous levels of NRBF2 protein.
W4BiowMW: ~ 40,34,26 kDa
Reactivity: Human,Rat,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human NRBF2.Alternative Name:
Nuclear receptor-binding factor 2; NRBF-2; Comodulator of PPAR and RXR; NRBF2; COPRWestern blot analysis: Western blot (WB) analysis of NRBF2 polyclonal antibody at 1:500 dilution LaneA:HepG2 whole cell lysate LaneB:L02 whole cell lysate LaneC:Aml-12 whole cell lysate LaneD:PC12 whole cell lysate LaneE:C6 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q96F24
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