Product Description
GPR143 polyclonal antibody is available at gentaur for next week delivery
Background: Guanine nucleotide-binding protein-like 3-like protein, stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Applications: WB IHC
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GNL3L polyclonal antibody detects endogenous levels of GNL3L protein.
W4BiowMW: ~ 72 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human GNL3L.Alternative Name:
Guanine nucleotide-binding protein-like 3-like protein; GNL3LWestern blot analysis: Western blot (WB) analysis of GNL3L polyclonal antibody at 1:500 dilution LaneA:H1792 whole cell lysate LaneB:MCF-7 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9NVN8
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