Product Description
GPR142 polyclonal antibody is available at gentaur for next week delivery
Background: Gas8 (growth arrest-specific 8), also known as Gas11, is a 478 amino acid protein that localizes to the Golgi apparatus, as well as to the cytoplasm and the flagellar basal body, and belongs to the growth arrest-specific protein family. Expressed in liver, heart and skeletal muscle with lower levels present in lung, brain, kidney and placenta, Gas8 functions as a cytoskeletal linker that binds microtubules and is thought to play a role in axonemal and non-axonemal dynein regulation. Gas8 may also be involved in spermatozoa motility and, when defective, may be associated with infertility in males lacking gametocytes. The gene encoding Gas8 maps to a region on human chromosome 16 that is frequently deleted in breast and prostate cancer, suggesting a role for Gas8 in tumorigenesis.
Applications: WB IHC
Purification&Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GAS8 polyclonal antibody detects endogenous levels of GAS8 protein.
W4BiowMW: ~ 56 kDa
Reactivity: Human,Rat,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human GAS8.Alternative Name:
Dynein regulatory complex subunit 4; Growth arrest-specific protein 11; GAS-11; Growth arrest-specific protein 8; GAS-8; GAS8; DRC4;GAS11Western blot analysis: Western blot (WB) analysis of GAS8 polyclonal antibody at 1:500 dilution LaneA:L02 whole cell lysate LaneB:The heart tissue lysate of Mouse LaneC:The heart tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O95995
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