Product Description
GPR125 polyclonal antibody is available at gentaur for next week delivery
Background: G-protein coupled receptor 158 (GPR158) is a receptor belonging to the Class C GPCR family. It lacks the extracellular Venus flytrap module characteristic of the known members of that family and instead contains two other elements that are not typical of the class: a calcium-binding EGF-like domain and a leucine repeat region. The mature extracellular domain of human GPR158 contains 393 amino acids (aa) and shares 89% identity with both mouse and rat GPR158. GPR158 is expressed at the highest level in the brain, but also in a variety of other tissues including retina, spleen, liver and lung. GPR158 was originally identified in functional screens linked with biological stress and has been implicated in the osteocalcin effect on cognitive processes in the brain, and glaucoma and cancer in the periphery.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GPR158 polyclonal antibody detects endogenous levels of GPR158 protein.
W4BiowMW: ~ 150 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human GPR158.Alternative Name:
Probable G-protein coupled receptor 158; GPR158; KIAA1136Western blot analysis: Western blot (WB) analysis of GPR158 polyclonal antibody at 1:500 dilution LaneA:BV2 whole cell lysate LaneB:PMVEC whole cell lysate LaneC:A549 whole cell lysate LaneD:HepG2 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q5T848
"
