Product Description
GLUT1 Rabbit monoclonal antibody is available at gentaur for next week delivery
Background: Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane, and shows a much less dramatic translocation in response to insulin.
Applications: WB ICC/IF IHC FC
Purification&Purity: Protein A affinity purified
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This antibody detects endogenous levels of GLUT1 and does not cross-react with related proteins.
W4BiowMW: ~ 54 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant antibody.Alternative Name:
GLUT1; Glucose transporter type 1. erythrocyte/brain; GLUT-1; GT1; Slc2a1; Glut-1; Glut1Western blot analysis: Western blot (WB) analysis of GLUT1 Rabbit mAb at 1:1000 dilution Lane1:Hela whole cell lysate Lane2:MCF-7 whole cell lysate Lane3:Jurkat whole cell lysate Lane4:NIH/3T3 whole cell lysate
Immunohistochemistry: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUT1 antibody. Counter stained with hematoxylin.
Immunofluorescence analysis: ICC staining GLUT1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.
Host: Rabbit
Swiss-Prot: P11166
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