Product Description
GLUD1 polyclonal antibody is available at gentaur for next week delivery
Background: This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GLUD1 polyclonal antibody detects endogenous levels of GLUD1 protein.
W4BiowMW: ~ 50 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant protein of human GLUD1.Alternative Name:
GDH; GDH1; GLUD;Western blot analysis: Western blot analysis of extracts of various cell lines, using GLUD1 antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded human colon using GLUD1 antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded human prostate using GLUD1 antibody at dilution of 1:200 (40x lens).
Host: Rabbit
Swiss-Prot: P00367
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