FYB polyclonal antibody

Product Description

FYB polyclonal antibody is available at gentaur for next week delivery

Background: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  FYB polyclonal antibody detects endogenous levels of FYB protein.

W4BiowMW:  ~ 110 kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to Human FYB.

Alternative Name:

ADAP; p120/p130; FYB1; FYB; SLAP130; Adhesion and degranulation promoting adaptor protein;; Fyb; FYB-120/130; FYN binding protein; FYN-binding protein; FYN-T-binding protein; SLAP-130; SLAP130; SLP-76-associated phosphoprotein

Western blot analysis:  Western blot (WB) analysis of FYB polyclonal antibody at 1:500 dilution LaneA:H9C2 whole cell lysate LaneB:SP2/0 whole cell lysate LaneC:PC3 whole cell lysate

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: O15117

 

 

 

 

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