Product Description
FOXO3 (Phospho-S315) polyclonal antibody is available at gentaur for next week delivery
Background: FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FOXO3 (Phospho-S315) polyclonal antibody detects endogenous levels of FOXO3 protein only when phosphorylated at Ser315.
W4BiowMW: ~ 82, 97 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human FOXO3 around the phosphorylation site of Serine 315.Alternative Name:
Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3AWestern blot analysis: Western blot (WB) analysis of FOXO3 (Phospho-S315) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:NIH3T3 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O43524
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