Product Description
FKBP3 polyclonal antibody is available at gentaur for next week delivery
Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Applications: WB IF IP
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FKBP3 polyclonal antibody detects endogenous levels of FKBP3 protein.
W4BiowMW: ~ 30 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human FKBP3.Alternative Name:
Peptidyl-prolyl cis-trans isomerase FKBP3; PPIase FKBP3; 25 kDa FK506-binding protein; 25 kDa FKBP; FKBP-25; FK506-binding protein 3; FKBP-3; Immunophilin FKBP25; Rapamycin-selective 25 kDa immunophilin; Rotamase; FKBP3; FKBP25Western blot analysis: Western blot analysis of extracts of various cell lines, using FKBP3 antibody.
Immunohistochemistry: Immunofluorescence analysis of HeLa cell using FKBP3 antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis: Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug FKBP3 antibody.
Host: Rabbit
Swiss-Prot: Q00688
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