Product Description
ELAC2 polyclonal antibody is available at gentaur for next week delivery
Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ELAC2 polyclonal antibody detects endogenous levels of ELAC2 protein.
W4BiowMW: ~ 105 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human ELAC2.Alternative Name:
Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2; ELAC2; HPC2Western blot analysis: Immunofluorescence analysis of A549 cell using ELAC2 antibody. Blue: DAPI for nuclear staining.
Immunohistochemistry: Western blot analysis of extracts of various cell lines, using ELAC2 Antibody.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9BQ52
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