DTL polyclonal antibody

Product Description

DTL polyclonal antibody is available at gentaur for next week delivery

Background: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), FBXO18/FBH1 and KMT5A. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication.

Applications:  WB

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  DTL polyclonal antibody detects endogenous levels of DTL protein.

W4BiowMW:  ~ 90 kDa

Reactivity: Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Alternative Name:

Western blot analysis:  Western blot analysis of extracts of various cell lines, using DTL antibody.

Immunohistochemistry:

Immunofluorescence analysis:

Host:  Rabbit