Product Description
DKK3 polyclonal antibody is available at gentaur for next week delivery
Background: Dickkopf-related protein 3, antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DKK3 polyclonal antibody detects endogenous levels of DKK3 protein.
W4BiowMW: ~ 55 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human DKK3.Alternative Name:
Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3; DKK3; REIC; UNQ258; PRO295Western blot analysis: Western blot (WB) analysis of DKK3 polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:A549 whole cell lysate LaneC:C6 whole cell lysate LaneD:The Brain tissue lysate of Mouse
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9UBP4
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