Product Description
DGK-α (A340) polyclonal antibody is available at gentaur for next week delivery
Background: Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-alpha influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-beta is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-gamma encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-delta is most abundant in skeletal muscle. DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol and is expressed predominantly in testis. DGK-zeta is most abundant in brain and muscle. DGK-eta is closely related to DGK-delta. DGK-theta is most abundant in the cerebellum and hippocampus.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DGK-α (A340) polyclonal antibody detects endogenous levels of DGK-α protein.
W4BiowMW: ~ 90 kDa
Reactivity: Human,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 310-360 of Human DGK-α.Alternative Name:
Diacylglycerol kinase alpha; DAG kinase alpha; 80 kDa diacylglycerol kinase; Diglyceride kinase alpha; DGK-alpha; DGKA; DAGK; DAGK1Western blot analysis: Western blot (WB) analysis of DGK-α (A340) pAb at 1:2000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:U-87MG whole cell lysate(40ug) Lane3:Myla2059 whole cell lysate(40ug) Lane4:HuT78 whole cell lysate(10ug)
Immunohistochemistry: Immunohistochemistry (IHC) analyzes of DGK-α (A340) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P23743
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