Product Description
Cytokeratin 8 (Phospho-S432) polyclonal antibody is available at gentaur for next week delivery
Background: Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Cytokeratin 8 (Phospho-S432) polyclonal antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at Ser432.
W4BiowMW: ~ 55 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human Cytokeratin 8 around the phosphorylation site of Serine 432.Alternative Name:
Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; Short name=K8; Type-II keratin Kb8; KRT8; CYK8Western blot analysis: Western blot (WB) analysis of Cytokeratin 8 (Phospho-S432) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:A549 whole cell lysate LaneC:The Lung tissue lysate of Mouse LaneD:The Liver tissue lysate of Mouse LaneE:The Lung tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P05787
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