Product Description
CYP39A1 polyclonal antibody is available at gentaur for next week delivery
Background: 24-hydroxycholesterol 7-alpha-hydroxylase, a cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis (PubMed:25201972, PubMed:10748047). Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver (PubMed:25201972, PubMed:10748047). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CYP39A1 polyclonal antibody detects endogenous levels of CYP39A1 protein.
W4BiowMW: ~ 55 kDa
Reactivity: Human,Rat,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human CYP39A1.Alternative Name:
24-hydroxycholesterol 7-alpha-hydroxylase; Cytochrome P450 39A1; hCYP39A1; Oxysterol 7-alpha-hydroxylase; CYP39A1Western blot analysis: Western blot (WB) analysis of CYP39A1 polyclonal antibody at 1:1000 dilution Lane1:C6 whole cell lysate(40ug) Lane2:AML-12 whole cell lysate(40ug) Lane3:PC3 whole cell lysate(40ug) Lane4:Pancl whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(40ug) Lane6:HepG2 whole cell lysate(40ug)
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q9NYL5
"
