Product Description
Cyclin H (Phospho-T315) polyclonal antibody is available at gentaur for next week delivery
Background: Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Cyclin H (Phospho-T315) polyclonal antibody detects endogenous levels of Cyclin H protein only when phosphorylated at Thr315.
W4BiowMW: ~ 37 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human Cyclin H around the phosphorylation site of Threonine 315.Alternative Name:
Cyclin-H; MO15-associated protein; p34; p37; CCNHWestern blot analysis: Western blot (WB) analysis of Cyclin H (Phospho-T315) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:H1688 whole cell lysate LaneC:The Liver tissue lysate of Mouse LaneD:The Liver tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P51946
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