COL9A1 polyclonal antibody

Product Description

COL9A1 polyclonal antibody is available at gentaur for next week delivery

Background: The Collagen Type IX protein (also known as Collagen α1 Type IX) is encoded by the COL9A1 gene which possesses two promoter regions and codes for both a long chain Collagen Type IX protein expressed in the cartilage, and a shorter Collagen Type IX protein expressed in the cornea and vitreous. Collagen Type IX forms a heterotrimer with Collagen α2 Type IX and Collagen α3 Type IX. When it is expressed in hyaline cartilage, Collagen Type IX posseses a large N-terminal globular domain (NC4). The COL9A1 gene is also expressed in the human inner ear, and disruption of this gene in mice results in hearing loss, indicating the role of Collagen Type IX in hearing. Mutations in the COL9A1 gene are associated with multiple epiphyseal dysplasia (MED), a chondrodysplasia, in humans. Collagen Type IX is often co-localized with Collagen Type II, and may play a role in the interaction of fibrils between Collagen Type II and Collagen Type IX.

Applications:  WB IHC

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  COL9A1 polyclonal antibody detects endogenous levels of COL9A1 protein.

W4BiowMW:  ~ 65 kDa

Reactivity: Human,Mouse

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Alternative Name:

Western blot analysis:  Immunohistochemistry of paraffin-embedded human stomach using COL9A1 antibody at dilution of 1:100 (40x lens).

Immunohistochemistry: Western blot analysis of extracts of mouse skeletal muscle, using COL9A1 antibody.

Immunofluorescence analysis:

Host:  Rabbit