Product Description
COL1A1 polyclonal antibody is available at gentaur for next week delivery
Background: COL1A1 comprises the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in COL1A1 are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Mutations in this protein are also associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor (1).
Applications: WB IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: COL1A1 polyclonal antibody detects endogenous levels of COL1A1 protein.
W4BiowMW: ~ 140 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
A synthetic peptide of human COL1A1.Alternative Name:
Collagen alpha-1(I) chain; Alpha-1 type I collagenWestern blot analysis: Western blot analysis of extracts of SGC7901 cell line, using COL1A1 antibody.
Immunohistochemistry: Immunofluorescence - COL1A1 Rabbit pAb
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P02452
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