CNPase (A108) polyclonal antibody

Product Description

CNPase (A108) polyclonal antibody is available at gentaur for next week delivery

Background: CNPase (2',3'-Cyclic Nucleotide 3'-Phosphodiesterase) exists in two forms: 46kDa (CNP1) and 48kDa (CNP2). It is expressed at high levels by oligodendrocytes in the central nervous system and by Schwann cells in the peripheral nervous system and is virtual absent in other cell types. CNPase activity is decreased in demyelinating diseases such as multiple sclerosis. CNPase gene is localized to chromosome 17q21, very near the BRCA 1 familial breast cancer gene.

Applications:  WB IHC

Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability:  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity:  CNPase (A108) polyclonal antibody detects endogenous levels of CNPase protein.

W4BiowMW:  ~ 47 kDa

Reactivity: Human,Mouse,Rat

Note:  For research use only, not for use in diagnostic procedure.

Immunogen:

Synthetic peptide, corresponding to amino acids 61-110 of Human CNPase.

Alternative Name:

2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP

Western blot analysis:  Western blot (WB) analysis of CNP pAb at 1:1000 dilution Lane1:The Brain tissue lysate of Mouse(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:CT-26 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug) Lane5:K562 whole cell lysate(40ug)

Immunohistochemistry: Immunohistochemistry (IHC) analyzes of CNPase (A108) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Immunofluorescence analysis:

Host:  Rabbit

Swiss-Prot: P09543

 

 

 

 

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