Product Description
CHI3L1 polyclonal antibody is available at gentaur for next week delivery
Background: Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CHI3L1 polyclonal antibody detects endogenous levels of CHI3L1 protein.
W4BiowMW: ~ 43 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human CHI3L1.Alternative Name:
Chitinase-3-like protein 1; 39 kDa synovial protein; Cartilage glycoprotein 39; CGP-39; GP-39; hCGP-39; YKL-40; CHI3L1; CGP39; GP39; hCGP39;Western blot analysis: Western blot analysis of extracts of THP1 cell lines, using CHI3L1antibody.
Immunohistochemistry: Immunohistochemistry of paraffin-embedded mouse liver using YKL-40 / CHI3L1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis: Immunohistochemistry of paraffin-embedded mouse spleen using YKL-40 / CHI3L1 antibody at dilution of 1:100 (40x lens).
Host: Rabbit
Swiss-Prot: P36222
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