Product Description
ChemR23 (R249) polyclonal antibody is available at gentaur for next week delivery
Background: Chemokine receptor-like 1 (also designated G protein-coupled receptor DEZ or ChemR23) belongs to the G protein-coupled receptor 1 family. It is an integral membrane protein functioning as a receptor, possibly a chemotactic peptide receptor. It also acts as a co-receptor for various SIV strains and for a primary HIV-1 strain. ChemR23 is highly expressed in developing osseous and cartilaginous tissue, brain, kidney, gastrointestinal tissues and myeloid tissue, as well as in adult parathyroid glands.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ChemR23 (R249) polyclonal antibody detects endogenous levels of ChemR23 protein.
W4BiowMW: ~ 50 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 216-265 of Human MChemR23.Alternative Name:
Chemokine-like receptor 1; G-protein coupled receptor; ChemR23; G-protein coupled receptor DEZ; CMKLR1; CHEMR23; DEZWestern blot analysis: Western blot (WB) analysis of CMKLR1 pAb at 1:500 dilution Lane1:RAW264.7 whole cell lysate(40ug) Lane2:PMVEC whole cell lysate(40ug) Lane3:HUT78 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug) Lane5:LO2 whole cell lysate(40ug)
Immunohistochemistry: Immunohistochemistry (IHC) analyzes of ChemR23 (R249) pAb in paraffin-embedded human kidney carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.
Immunofluorescence analysis: Immunohistochemistry (IHC) analyzes of ChemR23 (R249) pAb in paraffin-embedded human stomach carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.
Host: Rabbit
Swiss-Prot: Q99788
"
