Product Description
CHD2 polyclonal antibody is available at gentaur for next week delivery
Background: The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD proteins alter gene expression by modifying chromatin structure,thereby altering access of the transcriptional machinery to its chromosomal DNA template. Chromodomain helicase DNA binding protein 2, also known as CHD2, is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Consisting of 1,828 amino acids, CHD2 is expressed in the nucleus and contains two chromo domains, a helicase ATP-binding domain and a helicase C-terminal domain. CHD2 is suggested to play a critical role in development, hematopoiesis and tumor suppression. Mutations in the gene encoding CHD2 may be the cause of glomerulopathy, proteinuria and significantly impaired kidney function. CHD2 exists as two alternatively spliced isoforms.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CHD2 polyclonal antibody detects endogenous levels of CHD2 protein.
W4BiowMW: ~ 260 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Recombinant full length Human CHD2.Alternative Name:
Chromodomain-helicase-DNA-binding protein 2; CHD-2; ATP-dependent helicase CHD2; CHD2Western blot analysis: WesternBlot (WB) analysis of CHD2 polyclonal antibody
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O14647
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