Product Description
CH13L1 polyclonal antibody is available at gentaur for next week delivery
Background: YKL-40, also known as Chitinase-3-like protein 1 (CHI3L1), is a secreted glycoprotein encoded by the CHI3L1 gene . Unlike other members of the chitinase-like protein family, YKL-40 is not an active chitinase. It is produced by activated macrophages, chondrocytes, neutrophils, and synovial cells. It is a pro-inflammatory molecule that contributes to the progression of many inflammatory diseases, including fibrosis, neurodegenerative disease, breast, lung, prostate, liver, bladder, colon, and other types of cancers. Levels of YKL-40 in serum and plasma in patients with various types of tumors have been reported to predict poor prognosis, and in some clinical assays YKL-40 is being used as a predictive biomarker of cancer outcome.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CH13L1 polyclonal antibody detects endogenous levels of CH13L1 protein.
W4BiowMW: ~ 30-40kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human CH13L1.Alternative Name:
Chitinase-3-like protein 1;39 kDa synovial protein;Cartilage glycoprotein 39;CGP-39;GP-39;hCGP-39;YKL-40;CHI3L1Western blot analysis: Western blot (WB) analysis of CH13L1 polyclonal antibody at 1:2000 dilution Lane1:THP-1 whole cell lysate(40ug) Lane2:SHSY5Y whole cell lysate(40ug) Lane3:MCF-7 whole cell lysate(40ug) Lane4:Myla2059 whole cell lysate(40ug)
Immunohistochemistry: Immunohistochemistry of paraffin-embedded Human stomach cancer using CH13L1 antibody at dilution of 1:50 (40x lens).
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P36222
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