Product Description
CDYL2 polyclonal antibody is available at gentaur for next week delivery
Background: CDY is a gene family expressed exclusively in the testis that localizes to a region of the Y chromosome frequently deleted in infertile males. CDY proteins contain two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and a C-terminal domain, which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY proteins act as histone acetyltransferases with strong preference for Histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein 2 (CDYL2) is a related nuclear protein that is ubiquitously expressed with moderate levels in most tissues. The gene encoding CDYL2 is located on chromosome 16.
Applications: WB IHC ICC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CDYL2 polyclonal antibody detects endogenous levels of CDYL2 protein.
W4BiowMW: ~ 57 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human CDYL2.Alternative Name:
Chromodomain Y-like protein 2; CDY-like 2; CDYL2Western blot analysis: Western blot (WB) analysis of CDYL2 polyclonal antibody at 1:500 dilution LaneA:CT26 whole cell lysate LaneB:PC12 whole cell lysate LaneC:Hela whole cell lysate LaneD:PC3 whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q8N8U2
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