Product Description
CD91 (Phospho-S4520) polyclonal antibody is available at gentaur for next week delivery
Background: Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
Applications: WB
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD91 (Phospho-S4520) polyclonal antibody detects endogenous levels of CD91 protein only when phosphorylated at Ser4520.
W4BiowMW: ~ 85 kDa
Reactivity: Human,Mouse,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human CD91 around the phosphorylation site of Serine 4520.Alternative Name:
LRP-1; A2MR; APOER; CD91; LRP1; Msi 1; Msi1; MSI1H; Musashi homolog 1; Musashi-1; Musashi1; RNA binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1Western blot analysis: Western blot (WB) analysis of CD91 (Phospho-S4520) polyclonal antibody at 1:500 dilution LaneA:The Brain tissue lysate of Rat LaneB:C6 whole cell lysate LaneC:L02 whole cell lysate LaneD:HEK293T whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: Q07954
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