Product Description
CD8B polyclonal antibody is available at gentaur for next week delivery
Background: The T cell receptor (TCR) is a heterodimer composed of either α and β or γ and δ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (αα or αβ) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD8B polyclonal antibody detects endogenous levels of CD8B protein.
W4BiowMW: ~ 30kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human CD8B.Alternative Name:
T-cell surface glycoprotein CD8 beta chain;CD8b;CD8BWestern blot analysis: Western blot (WB) analysis of CD8B polyclonal antibody at 1:1000 dilution Lane1:The spleen tissue lysate of mouse(40ug) Lane2:Myla2059 whole cell lysate(40ug)
Immunohistochemistry: Immunohistochemistry of paraffin-embedded Human stomach cancer using CD8B antibody at dilution of 1:50 (40x lens).
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P10966
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