Product Description
CD63 (K156) polyclonal antibody is available at gentaur for next week delivery
Background: CD63 (also known as LAMP-3, Melanoma-associated antigen ME491, TSPAN30, MLA1 and OMA81H) is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD63 (K156) polyclonal antibody detects endogenous levels of CD63 protein.
W4BiowMW: ~ 30 kDa
Reactivity: Human
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to amino acids 111-160 of Human CD63.Alternative Name:
CD63 antigen; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63; MLA1; TSPAN30Western blot analysis: Western blot (WB) analysis of CD63 (K156) pAb at 1:1000 dilution Lane1:Jurkat whole cell lysate(40ug) Lane2:SHSY5Y whole cell lysate(40ug) Lane3:A375 whole cell lysate(30ug)
Immunohistochemistry: Immunohistochemistry (IHC) analyzes of CD63 (K156) pAb in paraffin-embedded human lung carcinoma tissue.
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P08962
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