Product Description
CD61 polyclonal antibody is available at gentaur for next week delivery
Background: Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16α and 8β subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD61 polyclonal antibody detects endogenous levels of CD61 protein.
W4BiowMW: ~ 110 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human CD61.Alternative Name:
Integrin beta-3; Platelet membrane glycoprotein IIIa; Short name=GPIIIa; CD_antigen=CD61; ITGB3; GP3A; CD61; GPIIIaWestern blot analysis: Western blot (WB) analysis of CD61 polyclonal antibody at 1:500 dilution LaneA:The Kdney, tissue lysate of Rat LaneB:The Testis tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P05106
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