Product Description
CD144 polyclonal antibody is available at gentaur for next week delivery
Background: The cadherins are a family of Ca 2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD144 polyclonal antibody detects endogenous levels of CD144 protein.
W4BiowMW: ~ 98, 140 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic peptide, corresponding to Human CD144.Alternative Name:
CDH5; Cadherin-5; 7B4 antigen; VE-Cadherin; Vascular endothelial cadherin; CD144Western blot analysis: Western blot (WB) analysis of CD144 polyclonal antibody at 1:500 dilution LaneA:A375 whole cell lysate LaneB:U-87MG whole cell lysate LaneC:The Brain tissue lysate of Mouse LaneD:The Brain tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P33151
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