Product Description
CD142 (Phospho-S290) polyclonal antibody is available at gentaur for next week delivery
Background: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V, FV, proaccelerin, labile factor) is a 2196 amino acid, single chain glycoprotein that is cleaved by Thrombin to yield an active, Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates into a Prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF), also designated coagulation Factor III is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
Applications: WB IHC
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD142 (Phospho-S290) polyclonal antibody detects endogenous levels of CD142 protein only when phosphorylated at Ser290.
W4BiowMW: ~ 45 kDa
Reactivity: Human,Rat
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human CD142 around the phosphorylation site of Serine 290.Alternative Name:
Tissue factor; TF; Coagulation factor III; Thromboplastin; CD142; F3Western blot analysis: Western blot (WB) analysis of CD142 (Phospho-S290) polyclonal antibody at 1:500 dilution LaneA:The Brain tissue lysate of Mouse LaneB:The Lung tissue lysate of Mouse LaneC:The Liver tissue lysate of Mouse LaneD:The Liver tissue lysate of Rat
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: P13726
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