Product Description
Catenin delta 1 (Phospho-Y228) polyclonal antibody is available at gentaur for next week delivery
Background: The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.
Applications: WB IHC IF
Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Catenin delta 1 (Phospho-Y228) polyclonal antibody detects endogenous levels of Catenin delta 1 protein only when phosphorylated at Tyr228.
W4BiowMW: ~ 108 kDa
Reactivity: Human,Mouse
Note: For research use only, not for use in diagnostic procedure.
Immunogen:
Synthetic phosphopeptide derived from human Catenin delta 1 around the phosphorylation site of Tyrosine 228.Alternative Name:
Catenin δ1; Catenin delta-1; Cadherin-associated Src substrate; Short name=CAS; p120 catenin; p120(ctn); p120(cas); CTNND1; KIAA0384Western blot analysis: Western blot (WB) analysis of Catenin delta 1 (Phospho-Y228) polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate
Immunohistochemistry:
Immunofluorescence analysis:
Host: Rabbit
Swiss-Prot: O60716
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